Define (1). Structure- Activity Relationship (SAR), (2). Medicinal Chemistry, (3). Drug
[3 marks]Describe protein biosynthesis
[4 marks]Write the mode of action of Non-Steroidal Anti Inflammatory drugs (NSAID). Write the synthesis, SAR & metabolism of any one Salicylate NSAID.
[7 marks]Write the classifications, MOA of anti HIV drugs with one example
[3 marks]What are GMPs? Why GMP is important? What are the responsibilities
[4 marks]Define the term: Transamination. Discuss Urea cycle in detail.
[7 marks]What are hormones? Give the classification of hormones with their functions
[7 marks]Describe Drug PKa concept.
[3 marks]Write a note on Drug classification.
[4 marks]Write the classifications with examples of anti-amoebic drugs. Write the Synthesis of (i). Metronidazole, (ii). Diloxanide Furoate. Write the MOA of any one drug.
[7 marks]What are (1). Diagnostic agents, (2). Antiseptics, (3). Disinfectants. Give one example for each category.
[3 marks]What is the medical condition called “Gout”? How the anti-gout agents work?. Give suitable example with structures.
[4 marks]Write the synthesis of (i). Ethambutol & (ii). Isoniazid. Write the MOA & metabolism of any one drug.
[7 marks]Write the MOA & synthesis of any one Sulphonamide drug
[3 marks]Describe the MOA & synthesis of any one alkylating agent anti- neoplastic drug.
[4 marks]Define drug metabolism. Write its importance. Describe the pathways with suitable example.
[7 marks]What are the classifications of Azole class of antifungal agents? Give one example in each class & Write the MOA of Azole antifungal agents.
[3 marks]What are the limitation in Cancer chemotherapy. Write a note on anticancer drug derived from plants. Write the MOA of any one drug.1
[4 marks]Explain in detail-Role of Vitamin as Coenzyme.
[7 marks]Discuss Photosynthesis in detail
[3 marks]What are Anthelminitics? Give one example with structure of any one Benzimidazole anthelminitics. Write its MOA & metabolism.
[4 marks]What is Glycolysis? Explain Glycolysis in detail with ATP synthesis
[7 marks]Describe the viral life cycle.
[3 marks]Write the SAR of 4-aminoquinoline antimalarial drugs. Give suitable examples.
[4 marks]Draw a neat labeled structure of Eukaryotic cell. Describe the function of cell organelles.
[7 marks]