Give WHO definition of Hypertension and classify it. Discuss pathophysiology of Hypertension and explain mechanism of action of β blockers in its treatment.
[6 marks]Discuss mechanism of action, adverse effects and therapeutic uses of Heparin. Name two Low Molecular Weight Heparins(LMWH)
[5 marks]Write a short note on: Oral Contraceptives.
[5 marks]Discuss the risk factors, pathophysiology and diagnostic tests for Diabetes Mellitus. Explain the mechanism of action of Sulphonylureas.
[6 marks]Classify diuretics giving examples of each class and explain mechanism of action of Loop Diuretics.
[5 marks]Write a short note on: Erectile dysfunction.
[5 marks]Classify Acute Renal Failure (ARF) based on etiology. Discuss its signs and symptoms and treatment.
[6 marks]Define Oxytocics. Give therapeutic uses of prostaglandins as oxytocic agents.
[5 marks]Write a short note on: Coronary Artery Bypass Graft Surgery (CABG) and Percutaneous Transluminal Coronary Angioplasty (PTCA).
[5 marks]Discuss the two systems of lipid transport and metabolism in the body. Give etiology of Hyperlipidaemia and explain the mechanism of Simvastatin as antihyperlipidemic agent.
[6 marks]Classify Anemia based on etiology. Write a short note on Iron Deficiency Anemia (IDA).
[5 marks]Write a short note on: Fibrinolytic agents.
[5 marks]Discuss the pathophysiology, clinical presentation and diagnosis of Angina Pectoris. Justify the use of Nitrates in treatment of angina.
[6 marks]Justify explaining mechanism of action the use of:
[5 marks]Enalepril in treatment of CCF (ii) Streptokinase as fibrinolytic agent
[ marks]Write a short note on: Megaloblastic anemia. Q. 6 (a) Define and classify Obesity. Discuss its diagnosis and treatment.
[6 marks]Discuss the pathophysiology, clinical features and tests for diagnosis of Congestive Cardiac Failure (CCF).
[5 marks]Write a short note on: Thrombosis
[5 marks]Explain the mechanisms of development of arrhythmias and classify antiarrhythmic agents based on mechanism of action.
[6 marks]Discuss the mechanism of action, pharmacological actions and therapeutic uses of Oestrogens.
[5 marks]Write a short note on: Long term complications of Diabetes Mellitus.
[5 marks]