Define: (1). Docking (2) Lead (3) Hit
[3 marks]Describe the procedure of Aseptic transfer
[4 marks]Explain culture preservation in detail
[7 marks]Classify H1 antihistamine with one example in each class.
[3 marks]Write a note on Antacids.
[4 marks]Write the SAR of H1 antihistamines Illustrate with suitable examples
[7 marks]Write synthesis and MOA of (1). Lidocaine, (2). Warfarin
[7 marks]What is “High Throughput Screening”?
[3 marks]Explain the steps involved in drug discovery process with a schematic diagram.
[4 marks]Define QSAR. What are the parameters used in QSAR studies.
[7 marks]Explain “Lipinski’s rule of 5”.
[3 marks]What are the principle governing “Computer Aided Drug Design”? Explain in detail
[4 marks]Explain the 4 phases involved in clinical trials.
[7 marks]What are local anesthetics? Write its classifications with one example in each class.
[3 marks]Write a note on (1). Thrombolytics, (2). Antiplatelet drugs. Write the synthesis of any one antiplatelet drug
[4 marks]Write short notes on (1). Radioimmunoassay, (2).Scanning & Transmission electron microscope
[7 marks]Write a note on Antiulcer drugs. Write a note on Proton pump inhibitor antiulcer drugs. Give suitable examples.
[3 marks]Write the synthesis of (1).Chlorcylizine, (2)Diphenhydramine HCl
[4 marks]Discus the Principle and Process of Acid Fast staining Technique
[7 marks]Explain the morphology of bacteria
[3 marks]Explain the concept of allergy
[4 marks]Describe Gram staining
[7 marks]Define: (1). Taxonomy, (2). Slime layer, (3). Plasmid
[3 marks]Briefly explain the motility detection test.
[4 marks]Describe the classification of culture media.
[7 marks]