What is polymorphic ventricular tachycardia (PVT)? Explain the etiopathogenesis of PVT.
[6 marks]Identify and explain the obstacles that contribute to the irrational use of drugs.
[4 marks]Define the following: 1. Preload 2. White-coat Hypertension 3. Afterload 4. Blood Pressure
[4 marks]Discuss the role of HMG CO-Areductase inhibitors and fibrates in the management of hyperlipidaemia.
[6 marks]Differentiate between Chronic Bronchitis and Emphysema based on their clinical manifestations.
[4 marks]Define Hyperosmolar hyperglycemic state (HHS). Explain the complications of HHS.
[4 marks]Differentiate between ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI).
[6 marks]List the drugs that cause QT prolongation.
[4 marks]Explain briefly thyrotoxicosis and Thyroid storm.
[4 marks]What is diabetic ketoacidosis? Explain the management of DKA.
[6 marks]Enumerate five common combination oral contraceptive regimens.
[4 marks]Write a brief note on the following: 1. Osteoclast 2. T – score
[4 marks]Explain in detail the management of myxedema coma.
[6 marks]Explain the treatment objectives of hormone replacement therapy (HRT) in post-menopausal women.
[4 marks]Write the following formula to calculate dosage regimen in pediatric patients: 1. Young's formula 2. Dilling's formula Q. 6 (a) Explain the categorization of drugs in pregnancy with two suitable examples for each category.
[6 marks]Justify why chloramphenicol is contraindicated in paediatrics.
[4 marks]Explain the following terminologies: 1. Rational drug use 2. Intraocular pressure (I.O.P)
[4 marks]Enumerate the distinguishing characteristics of open-angle and closed-angle glaucoma.
[6 marks]Describe the fundamental principles of essential drugs and outline the criteria used to determine whether a drug should be included in the essential drugs list.
[4 marks]Explain the pharmacotherapy of bacterial conjunctivitis.
[4 marks]