Discuss pharmaceutical application of colloids. Differentiate various types of colloidal dispersion system.
[6 marks]Explain: Kraft point and gold number.
[5 marks]Explain kinetic properties of colloids.
[5 marks]Discuss the concept of DLVO theory along with the energy curve and explain how this theory is applied in stabilizing the colloidal dispersion.
[6 marks]What is the effect of plug flow in measurement of viscosity of a plastic system, in cup and bob viscometer? How plug flow can be minimised?
[5 marks]Write a note on thixotropy.
[5 marks]Discuss non-Newtonian flow with rheogram, mechanism and explain with suitable example.
[6 marks]Describe a suitable viscometer with diagram which can measure the viscosity of dispersion of sodium alginate in water.
[5 marks]Define suspension. Differentiate between flocculated and deflocculated suspension.
[5 marks]Discuss different approaches used to achieve flocculation in suspensions.
[6 marks]Explain sedimentation parameter of suspension in detail.
[5 marks]Enlist the physical instability markers of emulsion and discuss any two.
[5 marks]Enlist the different type of densities of powder. Write the experimental method for the determination of true density.
[6 marks]Explain method for determining particle surface area.
[5 marks]Give factors affecting powder flow. Q. 6 (a) Enlist methods of particle size estimation. Explain conductivity method in detail.
[6 marks]Discuss angle of repose and Carr’s Index with their pharmacopoeial specification.
[5 marks]Write a short not on accelerated stability study.
[5 marks]Describe the various methods of determination of reaction order.
[6 marks]Explain factors which govern the rate of chemical reaction.
[5 marks]Discuss the various means of stabilization of product which is sensitive to oxidation.
[5 marks]