Enlist different types of receptors and discuss Gprotein coupled receptors in detail.
[6 marks]Classify Parasympathomimetic agents and write a note on organophosphate poisoning.
[5 marks]Discuss the factors modifying drug action in detail.
[5 marks]Enlist the factors affecting drug absorption. Explain how lipid solubility and ionization of drug affects its absorption.
[6 marks]Classify General Anaesthetics. Discuss the stages of general anaesthesia with suitable diagram.
[5 marks]Discuss types of Glaucoma, pathophysiology and its drug treatment.
[5 marks]Differentiate between Phase Iand Phase II biotransformation reaction.
[6 marks]Enlist various routes of drug administration and discuss advantages and disadvantages of Oral route.
[5 marks]Write a note on Neurohumoral transmission.
[5 marks]Classify Local anaesthetics and write a detailed pharmacology of procaine.
[6 marks]Define the following terms:
[5 marks]Tolerance ii) Loading dose iii) Inverse agonist iv) Competitive antagonism v) Enzyme induction.
[ marks]Write on role of GABA as a neurotransmitter in CNS.
[5 marks]Classify drug interactions and discuss pharmacokinetic drug interactions with suitable examples.
[6 marks]Discuss Mechanism of action and pharmacological actions of Adrenaline.
[5 marks]Explain the pharmacology of β- Blockers in detail. Q. 6 a) Classify Skeletal muscle relaxants. Explain mechanism of action and pharmacology of d- tubocurarine.
[6 marks]Discuss the rationale for the use of ethyl alcohol in methyl alcohol poisoning.
[5 marks]Classify antiepileptic drugs and write MOA and adverse effect of Phenytoin.
[5 marks]Classify drugs used in Parkinsonism. Explain why Carbidopa is used in combination with Levodopa.
[6 marks]Classify antipsychotic agent and write a note on atypical antipsychotic agents.
[5 marks]Differentiate between REM and NREM sleep. Explain the mechanism of actions, pharmacological actions, adverse effects and use of benzodiazepines.
[5 marks]