Define tablets. Classify different type of tablets with examples.
[6 marks]What is class 100 area ? Explain the construction requirement for it.
[5 marks]i. Comment : Sterile products must pass pyrogen test. ii. Differentiate : Dry granulation and direct compression.
[3 marks]Write a short note on preparation of Water for Injection with quality control specification according to IP/US pharmacopeia.
[6 marks]Give the examples of binders used for tablet formation. Explain various stages of granulation process.
[5 marks]i. Differentiate: Disintegration and dissolution process. ii. Give four examples of antioxidants used to prepare aqueous injection. iii. Differentiate: Water for injection and Sterile water for injection 01
[2 marks]Define Base absorption capacity and bloom strength with respect to soft gelatin capsule. Explain its importance and methods used to measure it.
[6 marks]Write a short note on formulation and evaluation of eye ointments
[5 marks]i. Comment: Acidic compound has pKa less than 7. ii. What should be the temperature and humidity range of the area where the soft gelatin capsules are manufactured?
[3 marks]Explain the method in detail to prepare hard gelatin capsule shell.
[6 marks]What is polymorphism? Explain different types of polymorphs with suitable examples. Explain importance of polymorphism in dosage form development.
[5 marks]i. What is racemization? Explain its importance in context of preformulation studies with suitable example. ii. What is ostwald ripening? Explain it importance with respect to stability of dispersion system
[3 marks]Classify the propellants used to prepare aerosol products with suitable examples.
[6 marks]Explain following terms and remedies to prevent it: 1. Orange peel effect 2. Mottling 3. Cracking 4. Chipping 5. Lamination
[5 marks]i. Comment: Metered dose inhalers (MDI) are preferred for pulmonary aerosol drug delivery system. ii. Comment: Syrup IP and USP have same concentration of sugar. Q. 6 (a) Write a short note on evaluation of suspension.
[6 marks]Classify primary, secondary, and tertiary packaging materials with example.
[5 marks]i. Give four examples of Non-ionic emulsifiers ii. Comment: Eudragit Eis an enteric coating polymer. Page 1 of
[2 marks]What is BCS classification system? explain its importance with respect to dosage form development.
[6 marks]Write a short note on Fluidized bed coater.
[5 marks]i. Give four examples of disintegrating agent. ii. Comment: Pellets have better control over drug release compared to conventional tablets. Page 2 of
[2 marks]