Relation between molecular biology and bioinformatics.
[3 marks]Explain data management and data analysis.
[4 marks]Discuss various tools used for data mining of biological databases.
[7 marks]Highlight various alignment problems.
[3 marks]Explain the concept of scoring matrices.
[4 marks]Explain the concept and procedure involved in multiple sequence alignment.
[7 marks]What is phylogenetic analysis? How it is performed?
[7 marks]Write applications of pairwise sequence alignment.
[3 marks]Describe any four areas of bioinformatics.
[4 marks]Write different types of BLAST and their applications.
[7 marks]Write uses of microarray technology.
[3 marks]Comment on clustering gene expression profiles.
[4 marks]Write different types of FASTA and their applications.
[7 marks]Write a note on branches of proteomics.
[3 marks]How will you measure sequence detection efficiency?
[4 marks]Describe various methods of gene prediction.
[7 marks]Write applications of multiple sequence alignment.
[3 marks]Comment on evaluation of predicted structure.
[4 marks]Explain the concept and procedure involved in protein secondary structure prediction.
[7 marks]What are structure visualization tools?
[3 marks]How will you predict the protein function?
[4 marks]Explain the principle, procedure and uses of 2D-PAGE in the field of proteomics.
[7 marks]Write areas influencing drug discovery.
[3 marks]How will you study protein-protein interaction?
[4 marks]What are SNPs? Explain the role of SNPs in drug discovery.
[7 marks]