Draw structure for the following compounds. 1) trans-1-bromo-3-chlorocyclobutane 2) cis-3-chloro-1-butene 3) 2-bromo-4-chloropentane 4) 3-chloro-2-butanol 5) (S)-3-chloro-1-pentanol 6) (2S,3R)-3-methyl-2-pentanol
[6 marks]Write a Short note on stereochemistry of Biphenyls.
[5 marks]Define the following terms:
[5 marks]Specific Rotation ii) Racemic mixture iii) Configuration iv) Enantiomer
[ marks]Geometrical isomerism
[ marks]Explain the following reactions.
[6 marks]Kolbe reaction of Phenols ii) Michael addition
[ marks]Discuss with mechanism Perkin reaction to synthesize α, β-unsaturated carbonyl compounds.
[5 marks]What are Phenols? How phenols are prepared?
[5 marks]What do you mean by Neucleophilic aromatic substitution reaction? Give mechanism for Elimination –addition reaction for aryl halides.
[6 marks]Explain the Hofmann degradation of amides.
[5 marks]Explain the mechanism involved in Aldol condensation.
[5 marks]What do you mean by conformation? Discuss the stability and potential energy changes of all conformations for n-pentane considering bond between Cand C .23 1 of
[2 marks]How will convert the following.
[5 marks]Acetophenone to α-Phenyl ethyl alcohol. ii) Benzoyl chloride to Ethyl benzoate iii) Toluene to Benzylamine iv) Toluene to o-Bromotoluene
[ marks]Nitrobenzene to m-bromophenol
[ marks]What are Acid derivatives? Discuss the preparation and reactions of Esters.
[5 marks]Discuss the Neucleophilic addition reactions for carbonyl compounds.
[6 marks]What are nano particles? How nano particles are used in Pharmacy.
[5 marks]Give the structure of the following compounds:
[5 marks]3,5-Dinitrobenzoyl Chloride ii) p-hydroxyphenylacetic acid iii) N,N-Dimethylaminocyclohexane iv) o-Chloroanisole
[ marks]Ethyl isopropyl ketone
[ marks]What are heterocyclic compounds? Give the preparations and reactions of pyridine.
[6 marks]Give the structure of the following. 1) Pyrazine 2) Imidazole 3) Isoquinoline 4) Thiazole 5) Indole
[5 marks]Comment on the following.
[5 marks]Electrophilic substitution in Pyrrole occurs at 2nd position rather than 3rd position. ii) Thiophene is more basic than furan.
[ marks]Give preparation and reactions of diazonium salt.
[6 marks]Write a note on green chemistry.
[5 marks]Give applications of microwave synthesis in chemistry. 2 of
[2 marks]