Explain the following synthesis with reaction mechanism. 1. Fischer’s indole synthesis, 2. Skraup Quinoline synthesis.
[6 marks]Define stereoselective and stereospecific reactions. Explain with suitable examples.
[5 marks]Enumerate different derivatives of carboxylic acids. How are they prepared from carboxylic acids?
[5 marks]Comment on following. 1. Pyridine is less basic than aliphatic amines. 2. Thiophene is more basic than furan. 3. Trichloroacetic acid is more acidic than acetic acid.
[6 marks]Explain Hell Wolhard Zelinsky reaction with mechanism.
[5 marks]Write a note on Riemer Tiemann reaction.
[5 marks]Explain following terms giving suitable examples. 1. Configuration, 2. Chiral centre, 3. Mesomer, 4. Resolution, 5. Optical rotation, 6. Geometric isomers
[6 marks]How is phenol prepared? Give any two methods.
[5 marks]Write a note on conformational isomers of cyclohexane.
[5 marks]Give 1 preparation and 1 reaction of Thiophene, pyrrole, pyridine.
[6 marks]Enumerate methods for preparation of carboxylic acid. Explain any two methods from them.
[5 marks]What is diazonium salt? Give their preparation and reactions.
[5 marks]Give structure of following compounds. 1. Pyrazine 2. Furan 3. Isooxazole 4. Pyrimidine 5. Indole 6. Pyridine
[6 marks]Define nucleophilic aromatic substitution reaction. Explain benzyne mechanism.
[5 marks]Write about application of nanochemistry in pharmacy. Q. 6 (a) Define green chemistry. Explain the principles of green chemistry with suitable examples.
[6 marks]Write reaction and mechanism of aldol condensation.
[5 marks]Give structure of following compounds. 1. Phenyl acetic acid, 2. para toluidine, 3. Benzoyl chloride 4. Malonic acid, 5. Phthalic anhydride.
[5 marks]Describe the principle of microwave synthesis. Explain applications of microwave synthesis in chemistry.
[6 marks]Define α,β-unsaturated carbonyl compounds. Explain Michael addition reaction in detail.
[5 marks]Explain Hoffmann degradation of amide in detail.
[5 marks]