Explain GABA as CNS neurotransmitter.
[6 marks]Classify NSAIDs with examples. Explain the pharmacological actions and therapeutic uses of Aspirin.
[5 marks]Write a short note on: Stages of anaesthesia.
[5 marks]Ennumerate Affective disorders. Explain in brief signs and symptoms and diagnostic tests for depression.
[6 marks]Classify immunosuppressants. Write the mechanism of action, adverse effects and therapeutic uses of Ciclosporin.
[5 marks]Write a short note on: Pre- anaesthetic medications.
[5 marks]Discuss etiology, clinical signs and symptoms and pathophysiology of Parkinsonism. Explain why levodopa is given in combination with carbidopa in treatment of Parkinsonism.
[6 marks]Discuss the positive and negative symptoms of Psychoses or Schizophrenia.
[5 marks]Write a short note on: Drug dependance and abuse.
[5 marks]Classify antiepileptic drugs acting through GABA giving brief mechanism of each class. What is status epilepticus
[6 marks]Explain synthesis and metabolism of Uric acid. Discuss the mechanism of action of Colchicine and Probenacid in treatment of Gout.
[5 marks]Write a short note on: Selective COX-II inhibitors.
[5 marks]Explain the pathophysiology, clinical features and tests for diagnosis of Alzheimer’s disease.
[6 marks]What are Disease Modifying AntiRheumatic Drugs (DMARDs)? Give examples. Explain their role in treatment of Rheumatoid Arthritis.
[5 marks]Write a short note on: Morphine poisoning and its treatment. Q. 6 (a) Define Anxiety. Give its etiology and signs and symptoms. Explain the role of Benzodiazepines in treatment of anxiety.
[6 marks]Define Insomnia. Give its etiology and differentiate between REM and NREM sleep.
[5 marks]Write a short note on: Dopamine as CNS neurotransmitter.
[5 marks]Discuss etiology, signs and symptoms and diagnosis of Rheumatoid Arthritis.
[6 marks]Classify CNS stimulant drugs. Explain mechanism of action and therapeutic uses of Amphetamine.
[6 marks]Justify the use of:
[6 marks]Donepezil in treatment of Alzheimer’s disease. (ii) Ethyl alcohol in treatment of methyl alcohol poisoning
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