Enlist various routes of administration.
[3 marks]Explain role of pKa in absorption of drug with suitable example.
[4 marks]Discuss Phase –I & Phase-II reactions with suitable examples.
[7 marks]How diuretics will act on urinary system?
[3 marks]What is cell organelles? Draw the diagram of a cell and label its different parts.
[4 marks]Write the synthesis & MOA of the antifungal agent Econazole & Miconazole. Write a brief note on its process.
[7 marks]Give the classification of Sulfonamides on the basis of duration of action. Write the synthesis of Sulphanilamide.
[7 marks]Define the terms: Medicinal Chemistry , drug & Structure Activity Relationship
[3 marks]Enlist importance of GMP.
[4 marks]Explain Tri Carboxylic Acid (TCA) cycle in detail.
[7 marks]Write a note on Cardiac cycle.
[3 marks]Write a note on blood and its composition.
[4 marks]Describe the reactions in the synthesis of urea (with cycle).
[7 marks]Define the terms: Diagnostic agents and Antiseptics
[3 marks]Write the synthesis of Nimesulide (structure given)
[4 marks]Write the SAR of 4-amino Quinolines and its MOA. OR1
[7 marks]Write a note on Nephron.
[3 marks]What is the medical condition called “Gout”? How the anti-gout agents work? Give suitable example with structures.
[4 marks]Write a note on antileprotic drugs. Mention its classifications. Give one example from each class. Write the synthesis of any one antileprotic drug.
[7 marks]Describe Protein bio-synthesis.
[3 marks]Write the synthesis& MOA of Isoniazid-an anti-tubercular drug.
[4 marks]Draw the diagram of lower respiratory system and label its different parts with function.
[7 marks]Explain DNA, RNA, and Chromosome.
[3 marks]Write the mechanism of action of NSAIDs.
[4 marks]Draw the diagram of different parts of urinary system with their function.
[7 marks]