Introduction to Medicinal Chemistry, Biochemistry & — Winter 2020

What are selective COX-2 inhibitors? Give two examples.

Write the synthesis & Metabolism of Isoniazid-an anti-tubercular drug

What is the medical condition called “Gout”? How the anti-gout agents work? Give suitable example with structures.

Define the terms i).Drug ii). SAR iii). MOA

Write the Classification & mode of action of Azole class of antifungal agent.

Explain SAR and mode of action of Sulfonamides.

Define the terms i). Transamination ii). Deamination

Write the synthesis of Nimesulide

What is Glycolysis? Explain Glycolysis in detail with ATP Synthesis. Explain the Glycolysis pathway in detail.

Mention the differences between DNA & RNA

What are i). Diagnostic agents, ii). Antiseptics, iii). Disinfectants iv). Bacteriostatic activity and bactericidal activity Give one example for each category.

Describe Protein bio-synthesis.

Write a note on Nephron

How diuretics will act on urinary system

Draw the diagram of different parts of kidney with their function.

Explain composition and functions of blood in detail

Write a short note on Cardiac cycle.

Define Cell & Mention the functions of cell organells? Draw the diagram of a cell and label its different parts with function.

Define i). Acidity ii) Bascity iii) pKa

Mention the Physicochemical factors affecting drug absorption

Write a note on Route of drug administration

What is GMP? Mention its applications towards pharmaceutical industry

Write the pathway of β-Oxidation of Fatty acids

Define drug metabolism. Write its importance. Describe the pathways with suitable example1