Illustrate the major families of receptors and their signaling mechanism.
[6 marks]Briefly discuss phase 2 drug metabolism / biotransformation reactions.
[4 marks]Explain the various routes of drug administration.
[4 marks]Classify adrenergic beta blockers. Discuss pharmacological actions and therapeutic effects of adrenergic beta blockers.
[6 marks]Describe the location and actions mediated by cholinergic receptor subtypes.
[4 marks]Classify drugs used for treatment of parkinsonism. Explain the mechanism of action of any one class.
[4 marks]Discuss the mechanism of action, pharmacological actions, pharmacokinetics, and therapeutic uses of benzodiazepines.
[6 marks]Describe the pharmacological actions of morphine.
[4 marks]Write a note on cognition enhancer drugs.
[4 marks]Classify anti-hypertensive drugs. Discuss the mechanism of action of ACE inhibitors and calcium channel blockers.
[6 marks]Illustrate with the help of a diagram the utility of digitalis in treatment of congestive heart failure.
[4 marks]Explain in brief the mechanism of action of different classes of anti-anginal drugs.
[4 marks]Summarize the mechanism of action of various classes of drugs used for the treatment of type 2 diabetes.
[6 marks]Write a mote on the synthesis and actions of thyroid hormones.
[4 marks]Define (a) mucolytics, (b) antitussives, (c) autocoids and (d) anti-histaminics. Q. 6 (a) Enlist the drug classes for treatment of asthma. Discuss the pharmacology of leukotriene antagonists.
[6 marks]Compare the mechanism of action of nondepolarizing and depolarizing neuromuscular blockers.
[4 marks]Discuss the pharmacology of any one general anesthetic drug.
[4 marks]Write a note on 5-HT receptors and actions of 5-HT.
[6 marks]Discuss PPAR alpha agonists in the treatment of hyperlipidemia.
[4 marks]Write a note on acute and chronic toxicity studies.
[4 marks]