Define receptors. Classify them and explain mechanism of nuclear receptors.
[6 marks]Define anesthesia. Classify anesthetic agents stating their advantages and disadvantages.
[4 marks]Describe mechanism of action and therapeutic uses of -
[4 marks]Propranolol ii) Digitalis
[ marks]Classify parasympatholytics .Detail therapeutic uses of atropine.
[6 marks]Discuss pharmacological actions of alcohol.
[4 marks]Describe mechanism of action and therapeutic uses of -
Lignocaine ii) Amphetamine
[ marks]Discuss process of drug absorption.
[6 marks]Classify antihypertensive agents. Discuss mechanism of action of centrally acting antihypertensive agents.
[4 marks]Classify anticonvulsants and state their mechanism of action.
[4 marks]Give mechanism of action and therapeutic uses of-
[6 marks]L-dopa b) Selegiline c)Diazepam.
[ marks]Detail mechanism of action and pharmacological actions of morphine.
[4 marks]Explain the terms i) Expectorants ii) Anti-tussives.
[4 marks]Give mechanism of action and side effects of the following-
[6 marks]Clozapine b) Phenytoin c) Chlorpromazine .
[ marks]Give synthesis, metabolism and pharmacological actions of thyroid hormones.
[4 marks]Give mechanism of action and therapeutic uses of i) Atorvastatin ii) Clofibrate Q. 6 (a) Discuss mechanism of action and pharmacological actions of insulin
[6 marks]Classify CNS stimulants. Explain mechanism of action and pharmacological actions of strychnine.
[4 marks]Explain the mechanisms: i) Ethyl alcohol is given to treat methyl alcohol toxicity ii) MAO inhibitors should not be taken with tyramine rich food.
[4 marks]Explain different routes of drug administration.
[6 marks]Classify histamine antagonists and state their therapeutic uses.
[4 marks]Classify different oral contraceptives detailing their mechanism of action.
[4 marks]