Classify anticoagulants with examples and explain the pharmacology of heparin.
[4 marks]Classify antileprotic drugs and discuss about dapsone.
[4 marks]Explain mechanism of action, pharmacological effects and therapeutic uses of loop diuretics.
[6 marks]Give the mechanism of action and side effects of co-trimoxazole.
[4 marks]Write a note on oncogenes.
[4 marks]Explain gene transcription and various factors that regulate transcription.
[6 marks]Explain the mechanism of development of bacterial resistance to antibiotics.
[4 marks]What is chronic toxicity study? Explain its importance in preclinical studies.
[4 marks]Classify anti-neoplastic agents with examples. Discuss about alkylating agents.
[6 marks]What is DNA replication? Give its importance.
[4 marks]Write a short note on mechanism of action, therapeutic uses and adverse effects of aminoglycosides.
[4 marks]Discuss life cycle of malaria and give pharmacology of chloroquine.
[6 marks]Classify the immunosuppressant. Write the mechanism of action, adverse drug 0 reaction, and therapeutic uses of mycophenolate mofetil.
[6 marks]Write a note on reverse transcriptase inhibitors.
[4 marks]What is the mechanism of functioning of MAP kinase? Q. 6 (a) What is cell signaling? Explain any two kinase signal transduction pathway.
[6 marks]Describe about gene sequencing and mapping.
[4 marks]Give the rationale for the following combination:
[4 marks]Sulbactum with Imepenam b) INH, Rifampicin and Ethambutol
[ marks]Explain the mechanism of action, spectrum of activity, therapeutic uses and adverse reactions of: a) Ciprofloxacin b) Cefuroxime
[6 marks]Write mechanism of action, therapeutic uses and adverse reactions of fluoroquinolones.
[4 marks]Discuss pharmacology of Anthelmintic drugs.
[4 marks]