Classify diuretics. Discuss the mechanism and uses of spironolactone.
[6 marks]Write a note on plasma expanders.
[4 marks]Classify antiplatelet drugs. Discuss the mechanism and uses of Aspirin.
[4 marks]Discuss the mechanism and adverse effects of
[6 marks]Chloramphenicol (ii) Ofloxacin (iii) Co-trimoxazole.
[ marks]What is chronic toxicity? Write its importance in preclinical studies.
[4 marks]Outline the complete life cycle of malarial parasite. Discuss the use of “Co- artemether”.
Discuss the mechanism and uses of
[6 marks]Desmopressin (ii) Warfarin (iii) Abciximab
[ marks]What is Drug Resistance? Discuss the mechanism of it.
[4 marks]Discuss the complete pharmacology of mebendazole.
[4 marks]Classify anticancer agents. Discuss anti metabolites in detail.
[6 marks]Write a note on cephalosporins.
[4 marks]Write a note on cell cycle regulators.
[4 marks]Justify the following comments.
[6 marks]Sulphonamides are associated with kernicterus if administered in newborns. (ii) Pyridoxine should be given prophylactically with higher doses of isoniazide. (iii) Zidovudine and Stavudine should not be used in combination.
[ marks]Define Immunomodulator. Discuss in detail about cyclosporine.
[4 marks]Classify antifungal drugs. Discuss the mechanism and uses of ketoconazole. Q. 6 (a) Classify semisynthetic penicillins. Discuss the mechanism, uses and adverse effects of ampicillin.
[6 marks]Write a note on tumor suppressor gene.
[4 marks]Discuss the signaling transduction pathway of MAP kinase.
[4 marks]Write a note on protein synthesis.
[6 marks]Discuss the transcription regulator factors in prokaryotes.
[4 marks]Define mutation. Classify mutations.
[4 marks]