Classify antifungal agents. Write in detail about Fluconazole.
[6 marks]Write a detail note on Dapsone.
[4 marks]Explain in detail about chemotherapy of malaria.
[4 marks]Classify antiviral agents. Write mechanism of action, adverse effects and therapeutic uses of Acyclovir.
[6 marks]Write a note on Heparin antagonist.
[4 marks]Write a note on anthelmintic agents.
[4 marks]Explain in detail about DNA replication.
[6 marks]What are the vectors used in gene transfer?
[4 marks]Discuss the recombinant DNA technology
[4 marks]What is cell signaling? Explain any one kinase signal transduction pathway.
[6 marks]Define Gene therapy. Write about gene targeting.
[4 marks]Write a note on Mutation.
[4 marks]Classify diuretics with suitable example. Write pharmacological action and therapeutic uses of loop diuretics.
[6 marks]Explain in brief about pharmacology of anti-diuretics.
[4 marks]How is cancer caused? Classify the drugs used to treat cancer. Q. 6 (a) Write the mechanism of actions:
[6 marks]Acetazolamide (ii) Vasopressin (iii) Rifampicin.
[ marks]Comment: 1) Gray baby syndrome is a common adverse effect of Chloramphenicol. 2) Sulphonamides are associated with kernicterus if administered in newborns.
[4 marks]What are Plasma Expanders? Give its therapeutic uses.
[4 marks]What is mean by transcription? How it is regulated?
[6 marks]Classify the immunosuppressants and its clinical application.
[4 marks]Describe in detail the determination of sub acute and chronic toxicity.
[4 marks]