Define general anaesthesia. Write various phases of the general anaesthesia.
[6 marks]Classify receptors. Discuss signal transduction pathway of the nuclear receptor.
[5 marks]Explain various phases of the clinical trial.
[5 marks]Define adverse drug reaction. Explain Rawlins–Thompson classification of adverse drug reaction.
[6 marks]Enlist routes of drug administration. Write merits and demerits of parenteral route.
[5 marks]Write a note on myasthenia gravis.
[5 marks]Define drug absorption. Discuss various mechanisms of the drug transport across the membrane.
[6 marks]Classify anticholinesterases. Write therapeutic uses of the anticholinesterases.
[5 marks]Write a note on neuromuscular blocking agents.
[5 marks]Classify sympathomimetic. Write pharmacological actions of the adrenaline.
[6 marks]Define opioid analgesic. Write pharmacological actions of the morphine.
[5 marks]Justify the comments:
[5 marks]Lithium carbonate can be used as mood stabilizer.
[ marks]Levodopa is used in combination with carbidopa.
[ marks]Discuss physiological and pathological role of the serotonin.
[6 marks]Classify the anti-epileptic drugs. Write pharmacology of the phenytoin.
[5 marks]Explain microsomal enzyme induction and inhibition with suitable examples. Q. 6 (a) Define drug-drug interaction. Explain pharmacokinetics drug-drug interaction with suitable examples.
[6 marks]Classify anti-depressant drugs. Write pharmacology of the SSRI.
[5 marks]Write a note on neurohumoral transmission.
[5 marks]Explain the following terms;
[6 marks]Drug addiction, b) Drug abuse, c) Drug tolerance
[ marks]Classify local anaesthetic agents. Write mechanism of action and adverse effects of Lidocaine.
[5 marks]Define antagonism. Explain different types of antagonism with suitable examples.
[5 marks]