Discuss the combined use of antibiotics with suitable examples with emphasis on synergism and to prevent the emergence of resistance.
[6 marks]Describe biochemical mechanisms of resistance to antibiotics.
[5 marks]Define cough. Differentiate between Expectorants and Antitussive agents.
[5 marks]Classify antifungal agents based on their mechanism of action. Write the mechanism of action and adverse effect of amphotericin Band Capsofungin.
[6 marks]Classify antiviral drugs. Describe the pharmacology of acyclovir.
[5 marks]Describe clinical symptoms and management of Organophosphorus poisoning Describe the life cycle of the malarial parasite and write the mechanism of action
[5 marks]06 and adverse effects of drugs acting on various phases of the life cycle of the parasite.
[ marks]Explain the mechanism of action, adverse effects, and therapeutic uses of the following drugs (i.) Fluoroquinolone (ii.) Chloramphenicol.
[5 marks]Write a note on proton pump inhibitors.
[5 marks]What is HAART? Write a note on drugs used in the treatment of HIV infection.
[6 marks]Discuss treatment and management of diarrhea with emphasis on ORT.
[5 marks]Classify semi-synthetic penicillins. Write antibacterial spectrum and therapeutic uses of amoxicillin.
[5 marks]Explain in detail: (i.) Superinfection and (ii.) Chronopharmacology
[6 marks]Write the MOA of the following drugs: (i.) Metoclopramide (ii.) Mesalazine05 (iii.) Etofamide (iv.) Foscarnet (v.) Doxorubicin
[ marks]Enlist first-line drugs used in Tuberculosis and provide an overview of the DOTS strategy in India. Q. 6 (a) Define immunopharmacology and Classify immunosuppressant drugs. Explain the Mechanism of action of Cyclosporine.
[6 marks]Classify Laxatives. Explain Osmotic purgatives.
[5 marks]Classify cell cycle-specific inhibitors. Explain the mechanism of action and adverse effects of Vinca alkaloids.
[5 marks]Write a note on bacterial cell wall synthesis inhibitors.
[6 marks]Classify types of Leprosy. Write detailed pharmacology of Dapsone.
[5 marks]Explain the following terms: (i.) Gray baby syndrome (ii.) Kernictrus (iii.) Jarisch Herxheimer’s reaction (iv.) Fancony-like syndrome (v.) Crystaluria.
[5 marks]