Define: retention time, retention volume, HETP, copyright, trademark, validation
[6 marks]Explain various modes of HPLC along with stationary phases.
[5 marks]Write a brief note on supercritical fluid chromatography.
[5 marks]Write a detailed note on HPTLC.
[6 marks]List various method validation parameters and explain any three validation parameters.
[5 marks]List ideal requirements of sample injector. Explain rotary valve injector in HPLC.
[5 marks]Explain various characteristics of mobile phase to be kept in mind while selection of solvents in HPLC.
[6 marks]Explain in detail UV- Visible detector in HPLC.
[5 marks]Write a detailed note on columns used in GC.
[5 marks]Explain electron capture detector and flame ionization detector.
[6 marks]Write a brief note on Raman spectrophotometry.
[5 marks]Explain isotope dilution analysis.
[5 marks]Explain the principle and application of nephelometry and turbidimetry.
[6 marks]Describe theory and applications of Radioimmunoassay.
[5 marks]Write a detailed note on stationary phases used in GC. Q. 6 (a) Differentiate the following : 1. HPTLC and TLC 2. HPLC and GC
[6 marks]Explain Bragg’s law and application of X-ray diffraction.
[5 marks]Explain in detail hyphenation technique, LC-MS.
[5 marks]Explain the principle and instrumentation of X- ray diffraction spectroscopy.
[6 marks]Write a detailed note on GLP.
[5 marks]Explain briefly ISO 9000 standards.
[5 marks]