Explain following terms: (Any Six) (a) Radioactivity (b) Retention Volume (c) Resolution (d) Dead time (e) HETP (f) Capacity factor (G) Asymmetric factor
[6 marks]Discuss various types of derivatization in GC. Write in detail about derivatization reaction that improves stability of molecules.
[5 marks]Define GLP and enlist different principles of GLP. Explain any three principles in detail.
[5 marks]Define Scattering. Write a note on Nephlometry.
[6 marks]Define patent and discuss different steps involved in patent filling process.
[5 marks]What is Nuclear Chemistry? Write a note on Neutron Activation Analysis.
[5 marks]Define pre-conditioning. What is importance of pre-conditioning in HPTLC. Discuss sorbents used in HPTLC
[6 marks]Discuss role of ISO 9001:2000 in quality management system.
[5 marks]Write a note on Size Exclusion Chromatography.
[5 marks]Discuss various validation parameters for analytical method validation as per ICH guideline
[6 marks]List ideal requirements of detector for HPLC and explain UV-Visible detector in HPLC
[5 marks]Write short note on RIA.
[5 marks]What are the units for radioactivity measurement? Explain isotopes dilution analysis.
[6 marks]Write a note on temperature programming in GC.
[5 marks]Write a note on GATT & TRIPS.
[5 marks]What are Xrays? Derive Bragg's equation and enlist application of Xray diffraction.
[6 marks]Explain in brief about LC/MS –MS.
[5 marks]Explain the principle and instrumentation of Super Fluid Chromatography.
[5 marks]Differentiate: 1. Reverse and Normal phase chromatography 2. GC and HPLC 3. Capillary and Open tubular column Page 1 of
[2 marks]Write a short note on different types of ELISA technique.
[5 marks]Enlist different detector used in GC. Write a note on ECD. Page 2 of
[2 marks]