Define Nanoparticles. Write the applications of Nanotechnology in Pharmaceutical field.
[3 marks]Define Residual solvents. Write a note on the classifications of residual solvents based on the risk factors.
[4 marks]Explain in detail: Top down and bottom up approaches in nanoparticle generation.
[7 marks]Define Dendrimer and give its applications.
[3 marks]What are Gold nanoparticles? What are the applications of Gold nanoparticles?
[4 marks]List out the factors for choosing solvents. Describe any six of them.
[7 marks]Explain the Use of Calorimetry in addressing reaction safety. Illustrate with examples.
[7 marks]Differentiate Nanoparticles and Microparticles.
[3 marks]What are micelles? Write its applications & advantages in pharmaceutical drug delivery.
[4 marks]Describe the characterization tests for nanoparticles.
[7 marks]Define solid lipid nanoparticles & polymeric nanoparticles
[3 marks]Explain the zeta potential and particle size determination for nanoparticles.
[4 marks]Explain spray drying method with a neatly labeled diagram for nanoparticles formulation
[7 marks]What are Nanocapsule & Nanospheres. Draw their structures.
[3 marks]Write the advantages & disadvantages of nanoparticles. Write a note on supercritical fluid technology in nanoparticle preparation.
[4 marks]Describe two methods of resolution of racemates by direct crystallization with suitable examples.
[7 marks]Define: (1). Hydrogel nanoparticle, (2). Ceramic nanoparticle, (3). Functionalized naoparticle
[3 marks]List out the preparative methods for polymeric nanoparticles. Explain any one of them
[4 marks]List out the factors to be considered while choosing a filtration equipment. Describe any two filtration equipment with neatly labeled diagrams.
[7 marks]What is a “reagent”? Discuss the properties to be considered while selecting a reagent
[3 marks]Write a brief note on Marckwald principle & Reciprocal resolutions with example1
[4 marks]Describe: (1). Process safety failures and the consequences, (2). Definition, Theory and Factors affecting Adsorption
[7 marks]Write a note on Phase transfer catalyst. What are the factors to be considered while choosing a Phase Transfer Catalyst (PTC) & how selectivity in PTC can be achieved?
[3 marks]Define chiral auxiliary. Describe the use of chiral auxiliary with a schematic diagram. Write one example of the use of chiral auxiliary
[4 marks]Discuss the steps to be taken for the optimization of process. Illustrate with example.
[7 marks]