Process Technology of Drugs and Intermediates and — Winter 2023

What are super critical solvents? Give an example.

Describe Residual solvents with its classifications.

Discuss Top down and bottom-up approaches in nanoparticle synthesis.

What are Dendrimers?

What are gold nanoparticles? Give its applications.

What are the selection criteria for solvent selection?

List out the classifications of nanoparticles and explain them.

Differentiate Nanoparticles and Micro particles.

What are micelles and liposomes?

Explain spray drying method with neat, labeled diagram.

Define solid lipid nanoparticles & polymeric nanoparticles.

Describe the zeta potential and particle size determination for nanoparticles.

Explain Sol gel method with neat, labelled diagram.

Define: Nanocapsule & Nanospheres.

Describe supercritical fluid technology in nanoparticle preparation.

Explain the techniques for identifying exothermicity & gas evolution.

Give the applications of :(1) Solid-Lipid nanoparticle (2) Ceramic nanoparticle, (3) Gold nanoparticle

Write short notes on ultrafiltration & microfiltration.

What are the selection criteria for filtration equipment?

What is a “reagent”? Discuss the properties to be considered while selecting a reagent.

List out the preparative methods for polymeric nanoparticles. Explain any one of them.

Describe the Process safety failures and its consequences.

Write a note on Phase transfer catalyst.

What are the factors to be considered while choosing a Phase Transfer Catalyst (PTC) & how selectivity in PTC can be achieved?

Define chiral auxiliary with example. Describe the use of chiral auxiliary with a schematic diagram.