Detail various routes of drug administration stating their advantages and disadvantages.
[6 marks]Give mechanism of action and pharmacological actions of insulin.
[4 marks]Give therapeutic uses of a)Amantidine b)Lignocaine
[4 marks]State different types of receptors. Explain signaling transduction in Gprotein coupled receptors.
[6 marks]Define anesthesia. Give stages of anesthesia and characteristics of an ideal anesthetic agent.
[4 marks]Explain the terms :Bioavailability of a drug; Therapeutic index of a drug
[4 marks]Classify anti-hypertensive agents. Discuss the role of renin angiotensin system in regulating hypertension.
[6 marks]Classify anti-arrthymic drugs. Give pharmacology of amiodarone
[4 marks]Write a short note on Drug interactions.
[4 marks]Give pharmacological actions and therapeutic uses of alcohol.
[6 marks]Give pharmacological actions of histamine .Write therapeutic uses of anti- histaminic agents.
[4 marks]Explain the terms : Acute toxicity; Enzyme induction
[4 marks]Give mechanism of action and pharmacological actions of thyroid hormones.
[6 marks]Discuss absorption of a drug.
[4 marks]Give therapeutic uses of :a) Clozapine b)Propranolol Q. 6 (a) Classify parasympatholytics. Give therapeutic uses of anti-cholinergic agents.
[6 marks]Compare and contrast narcotic and non-narcotic analgesics.
[4 marks]Give mechanism of action and therapeutic uses of Diazepam.
[4 marks]Define epilepsy. Enumerate first and second drug of choice for different types of epilepsy
[6 marks]Give mechanism of action, therapeutic uses and side effects of Digitalis
[4 marks]Explain the terms: Volume of distribution ; Half-life of a drug
[4 marks]