Define drug-drug interaction. Discuss pharmacokinetic drug-drug interaction with examples.
[6 marks]Classify neuromuscular blocking agents. Write pharmacology of depolarizing blockers.
[4 marks]Enumerate antiarrhythmic drugs according to effect on action potential.
[4 marks]Describe mechanism of action, adverse drug reactions and therapeutic uses of aminophylline.
[6 marks]Classify antihistaminic drugs. Outline side effects and uses of Hblockers.2
[4 marks]Discuss preanesthetic medicines with their significance.
[4 marks]Justify following combinations: 1) Levodopa and Carbidopa 2) Local anesthetic and Epinephrine
[4 marks]Explain hepatic microsomal enzyme induction and inhibition with suitable examples.
[6 marks]Discuss therapeutic uses and adverse effects of β-blockers.
[4 marks]Classify antihypertensive drugs. Write pharmacology of angiotesin receptor blockers.
[6 marks]Write a note on methyl alcohol poisoning.
[4 marks]State mechanism of action and adverse effects of phenytoin.
[4 marks]Distinguish sedative and hypnotics. Outline disadvantages of barbiturates.
[4 marks]Discuss pharmacological actions of platelet activating factor (PAF).
[4 marks]What is receptor? Distinguish GPCR and nuclear receptor.
[6 marks]Enlist oral hypoglycemic agents. Give mechanism of action of SGLT-2 inhibitors.
[4 marks]Write a note on oral contraceptives. Q. 6 (a) Enlist routes of drug administrations. Give importance of each route.
[6 marks]Classify NSAIDs. Write mechanism of action and uses of aspirin.
[6 marks]Write a note on antitussive agents.
[4 marks]Enumerate lipid lowering drugs. Give mechanism of action and adverse effects of statins.
[4 marks]