Describe the solute - solvent interactions that influence the solubility of drugs in liquids.
[6 marks]Define & explain solubility. Discuss different solubility expressions.
[5 marks]Explain Henry’s law and factors affecting for solubility of gases in liquids.
[5 marks]Define & explain for the state of matter (i) Critical point (ii) Eutectic mixture.
[6 marks]Describe different types and applications of liquid crystals.
[5 marks]Write short note on polymorphism.
[5 marks]Define surface tension and express it in terms of surface free energy.
[6 marks]Describe capillary rise method to determine surface tension.
[5 marks]Write short note on spreading co-efficient.
[5 marks]Define complexes. Write applications of complexation in pharmacy.
[6 marks]Write short note on chelate type complexes.
[5 marks]Describe solubility method to determine the formation of complex and it’s stability constant.
[5 marks]Explain buffer & buffer capacity. Write applications of buffers in pharmacy.
[6 marks]Describe electrometric method to determine pH.
[5 marks]Explain isotonic solutions & paratonic solutions. Describe freezing point depression method for adjusting the tonicity of a solution. Q. 6 (a) Explain distribution law. Write it’s limitations and applications.
[6 marks]Explain Refractive Index. Write it’s applications.
[5 marks]Define Dielectric Constant. How it is measured?
[5 marks]Write short note on Hydrophilic - Lipophilic Balance (HLB).
[6 marks]Write short note on Langmuir adsorption isotherm.
[5 marks]Explain protein binding. Write importance of protein binding.
[5 marks]