Pharmaceutical Organic Chemistry III — Winter 2024

Write a note on Geometric isomerism in detail.

Explain Conformational isomers of Cyclohexane.

Discuss Rand S Configuration with example.

Write a note on Stereochemistry of biphenyl Compounds.

Explain Chemical reactions given by Furan.

Give Structure of i) indole ii) Pyridine iii)imidazole iv)Thiophene v)Quinoline

Explain any two methods of synthesis of purine and its medicinal uses.

Define(any five): i) Enantiomers ii) Atropiisomers iii) isomers iv)mesocompund v) Chirality vi) Racemic mixture

Discuss the sequence rule to assign configuration with example.

Give differance between Stereospecific and Streoselective reaction.

Explain any two methods for synthesis of Thiophene.

Write a note on reactions given by Chiral Molecules.

Explain i) Oppenauer oxidation reaction ii) Dakin reaction

Discuss chemical and Physical properties of Pyrazole.

Explain Relative aromaticity of Pyrrole, Furan and Thiophene Q. 6 (a) Write a note on Metal hydride reduction.

Explain preparation and reactions of Pyridine.

Give medicinal uses of Pyrazole and Imidazole.

Explain Clemmensen reaction in detail.

Discuss and compare basicity of pyridine, pyrrole and aliphatic Amines.

Justify(any two) : i) Electrophilic substitution takes place at 2-position in Pyrrole ii) Furan undergoes diels alder reaction iii) Furan has high boiling point than Pyrrole