What are sulfonamides ? Give their uses and adverse effects.
[6 marks]Write short notes on β -lactam antibiotics.
[5 marks]Give SAR of Penicillins.
[5 marks]Classify cephalosporins with examples.
[6 marks]What are fluoroquinolones. Write their SAR.
[5 marks]What are aminoglycosides ? Give their uses and mechanism of action.
[5 marks]Classify Anti-TB drugs with examples. Give their mechanism of action.
[6 marks]Give synthesis and SAR of Chloramphenicol.
[5 marks]Write short notes on Antiamoebic drugs.
[5 marks]Give life cycle of malarial parasite. Write SAR of Quinoline derivatives.
[6 marks]Classify antifungal agents and give their mechanism of action.
[5 marks]Write short notes on anti-HIV agents.
[5 marks]Give IUPAC name and synthesis of ;
[6 marks]Pyrimethamine (ii) Metronidazole (iii) Pyrazinamide.
[ marks]Write short notes on combinatorial chemistry.
[5 marks]Explain in brief about Anti viral agents. Q. 6 (a) What are Antineoplastic drugs ? Classify them with examples.
[6 marks]Write short notes on adverse effects of Anticancer drugs.
[5 marks]Give synthesis of Cyclophosphamide and Fluorouracil.
[5 marks]Explain Hansch linear free energy relationship model of QSAR.
[6 marks]Write short notes on Molecular modeling.
[5 marks]How lead optimization is done ?
[5 marks]