What are sulfonamides? Give their uses and adverse effects. Write synthesis of sulphamethoxazole
[6 marks]Give the synthesis of – 1) ciprofloxacin and 2) Cyclophosphamide
[5 marks]Describe in brief β-Lactamase inhibitors.
[5 marks]What are aminoglycosides? Give their uses and mechanism of action and SAR
[ marks]06 study.
[ marks]Give synthesis, therapeutic uses & mechanism action of chloramphenicol.
[5 marks]Explain the SAR of Tetracycline.
[5 marks]Give the life cycle of a malarial parasite. Write SAR of 4-Aminoquinoline?
[ marks]06
[ marks]Classify antifungal agents and give their mechanism of action
[5 marks]Write short notes on Antiamoebic agents.
[5 marks]Write a detailed note on anthelmintic agents. Give synthesis of albendazole.
[ marks]06
[ marks]Write the degradation of penicillin with structures.
[5 marks]Discuss in brief Antiviral agents. Give its mechanism of action with an example.
[5 marks]Draw the structure and give the uses of 1) Chlorambucil 2) Norfloxacin 3)
[ marks]06 Isoniazid 4) Thiotepa 5) Cephalosporin 6) Fluorouracil
[ marks]What are Antineoplastic drugs? Classify them with examples.
[5 marks]Write short notes on the adverse effects of Anticancer drugs.
[5 marks]Explain Hansch's linear free energy relationship model of QSAR. Q. 6
[6 marks]Write a detailed note on MDR-TB and XDR-TB.
[5 marks]Discuss in brief lead optimization
[5 marks]Write a detailed note on computer-aided drug design.
[ marks]Give an informative note on molecular modeling and its applications.
[5 marks]Write short notes on combinatorial chemistry.
[5 marks]