What are β-lactam antibiotics? Discuss Cephalosporins in detail.
[6 marks]Discuss SAR of Penicillins.
[5 marks]Write any two synthesis 1. Ciprofloxacin 2. Cholarmphenicol 3. Trimethoprim.
[5 marks]Discuss SAR of Fluoroquinolones with chemical structures.
[6 marks]Write a note on anthelmintics.
[5 marks]Give SAR of sulphonamides and synthetic scheme of sulphacetamide.
[5 marks]What are antineoplastic agents? Classify those agents.
[6 marks]Discuss macrolide antibiotic drugs in detail.
[5 marks]Write SAR of tetracyclines.
[5 marks]Give a detailed note on synthetic and antibiotic anti-fungal agents.
[6 marks]What are anti-mycobacterial agents? Classify them in detail with structures.
[5 marks]Write any two synthesis 1. Ethambutol 2. Ketoconazole 3. Metronidazole.
[5 marks]What are anti-malarial agents? Discuss SAR of Quinolines.
[6 marks]Write any two synthesis 1. Norfloxacin 2. Isoniazid 3. Clotrimazole.
[5 marks]Write a note on fluroquinolones. Q. 6 (a) Give Detailed note on following 1. Anti-protozoal agents 2. Anti-amoebic agents
[6 marks]Write classification of anti-viral and anti-HIV agents.
[5 marks]Write any two synthesis 1. Chloroquine 2. Cholrambucil 3. Tamoxifen.
[5 marks]Enlist various models of QSAR? Discuss Hansch Linear Free Energy Relationship (LFER) model in detail.
[6 marks]Write various methods of lead discovery and its optimization.
[5 marks]Write a note on following 1. Molecular Modeling 2. Combinatorial Chemistry
[5 marks]