What do you mean by chemotherapeutic agents? Give SAR of Cephalosporins.
[6 marks]What are Fluoroquinolones ? Give their SAR.
[5 marks]Write short notes on computer aided drug design.
[5 marks]Write detail SAR of Penicillins.
[6 marks]What are antitubercular agents? Briefly explain first line antitubercular agents.
[5 marks]Write short note on “Free Wilson Mathematical model of QSAR”
[5 marks]Define and classify Anti-neoplastic agents. Give the method of synthesis of Chlorambucil.
[6 marks]Give the method of synthesis & uses of i) Sulphacetamide ii) Ofloxacin
[5 marks]Define and classify Antiviral agent with suitable examples. Give the method synthesis of Amantadine.
[5 marks]Classify Antibiotics. Explain the SAR of β-Lactam antibiotic.
[6 marks]Give a detailed account of antiamoebic agents.
[5 marks]Give synthesis of the following drugs : (i) Fluorouracil (ii) Tamoxifen
[5 marks]Write a note on molecular modelling.
[6 marks]Write in detail about drugs used in HIV infection.
[5 marks]What is combinatorial chemistry? Discuss in detail about different methodologies used for synthesis in it. Q. 6 (a) Classify sulphonamide. Give synthesis of sulphamethoxazole.
[6 marks]Discuss in brief lead optimization.
[5 marks]Write synthesis of a) Albendazole b) Clotrimazole
[5 marks]Give the IUPAC name and synthesis of chloramphenicol.
[6 marks]Discuss in detail about degradation products of penicillin.
[5 marks]Discuss the chemistry of aminoglycoside antibiotics.
[5 marks]