Classify sulfonamide on the basis of chemical structure and explain biosynthetic pathway leading to THF synthesis with involvement of sulfonamides.
[6 marks]Explain SAR of fluoroquinolones.
[5 marks]Write chemical name and synthesis of sulfacetamide and norfloxacin.
[5 marks]Classify cephalosporin and represent various ring and numbering system of clinically available beta-lactam antibiotic types with examples.
[6 marks]Explain chemical instability of penicillin in detail.
[5 marks]Explain SAR activities of aminoglycoside antibiotics.
[5 marks]Give any three structures of macrolide antibiotics and explain why erythromycin is unstable in acid media.
[6 marks]Explain epimerization and degradation of tetracycline in detail.
[5 marks]Write a short note on carbapenem and monobactams.
[5 marks]Classify antimalarial agents with examples and structures.
[6 marks]Write chemical name and synthesis of primaquine and metronidazole.
[5 marks]Explain SAR activities of quinolines.
[5 marks]Explain XDR-TB. write a note on first-line anti TB agents.
[6 marks]Classify and explain mechanism of action of azole antifungal agents.
[5 marks]Write chemical name and synthesis of ketoconazole and isoniazid. Q. 6 (a) What is carcinoma? Classify anticancer agent with examples and structures.
[6 marks]Write a note on alkylating agents used as anticancer agent.
[5 marks]Write a note on antiviral agents.
[5 marks]Explain in detail molecular modeling.
[6 marks]Write a note on methods of lead discovery.
[5 marks]Write a note on QSAR.
[5 marks]