Write a note on ionotropic receptors.
[6 marks]Describe various theories of drug-receptor interaction.
[5 marks]Discuss the factors affecting the drug-receptor interaction.
[5 marks]Define xenobiotics. Describe any four oxidative reactions of phase-I metabolism.
[6 marks]Explain hydrolytic reactions of phase-Imetabolism with examples.
[5 marks]Define conjugation reactions of drug metabolism. Write about sulfate conjugation.
[5 marks]Describe the SAR of muscarinic antagonists.
[6 marks]Write the mechanism of action and one example with structure of reversible and irreversible anticholinesterases.
[5 marks]Write the synthesis of dicyclomine and isoprenaline.
[5 marks]Classify the sympatholytics with chemical structures.
[6 marks]Write a short note on ganglion blockers.
[5 marks]Discuss the structural modifications phenyl ring of phenylethanolamines.
[5 marks]Write a note on tricyclic antidepressants.
[6 marks]Define hallucinogens. Write the examples of them which are unrelated to monoamine neurotransmitters.
[5 marks]Write the synthesis and use of amphetamine and imipramine. Q. 6 (a) Explain the SAR of phenothiazines as antipsychotic drugs.
[6 marks]Classify the anxiolytics with chemical structures.
[5 marks]Write any two classes of antiepileptics.
[5 marks]What are opioid analgesics? Discuss about benzomorphan class of them.
[6 marks]Write the examples with structures of selective COX-II inhibitors.
[5 marks]Define DMARDs. Discuss gold compounds used as DMARDs.
[5 marks]