Define QSAR. Give brief account on Hansch QSAR model
[6 marks]Explain the terms: (i) CADD (ii) Antisense molecules
[4 marks]Give structure and mechanism of any two drugs from each (i) Antiscabies (ii) Antitubercular agents
[4 marks]Write a brief note on anti- HIV agents
[4 marks]What is crystalluria? Give synthesis of any one sulphonamde
[4 marks]Describe the SAR amino quinolines used as antimalarial
[6 marks]Describe the SAR of tetracyclines
[6 marks]Give brief account on Angiotensin II receptor antagonists
[4 marks]Give synthesis of (i) Atenolol (ii) Warfarin
[4 marks]Classify oral hypoglycemic agents
[6 marks]Give structures and mechanism of Statins
[4 marks]Give brief account on thyroid and antithyroid agents
[4 marks]Classify antianginal drugs. Give synthesis of nitroglycerine
[6 marks]Write a short note on antimetabolites as anticancer agents
[4 marks]Thiazides are weak diuretics- Justify the sentence. Give structure of any one loop diuretic Q. 6 (a) Classify female sex hormones. Enumerate various steroidal oral contraceptives
[6 marks]Explain the degradation of penicillin. Draw the structure of any two oral penicillins
[4 marks]Write a note about diagnostic agents and their applications
[4 marks]Give SAR of glucocorticoids
[6 marks]Give synthesis of (i) Cyclophosphamide (ii) Metformin
[4 marks]Give adverse effects and synthesis of chloramphenicol
[4 marks]