Medicinal Chemistry — Summer 2025

Define hyperlipidemia. Define and classify antihyperlipidemic agents with at least two drug names and one structure of each category.

Write a short note on ACE inhibitors with its mechanism of action in detail.

Define angina and antianginal agents. Discuss in detail about nitrates and nitrites with its mechanism of action, three drug names and structure that comes under nitrates and nitrites family.

Define and classify antiviral agents with at least two drug names and one structure of each category.

Give SAR on fluoroquinolones.

Share your idea about antiarrhythmic agents.

Define and classify antineoplastic agents with at least two drug names and one structure of each category.

Write a short note on oral hypoglycemic agents.

Give SAR on adrenocorticoids.

Write note on combinatorial chemistry.

Give synthesis of: (any two)

. Sulphamehoxazole ii). Isoniazid iii). Ketoconazole iv). Propranolol.

Give SAR on Tetracyclines.

Write a short note on antithyroid agents. Give synthesis of Carbimazole.

Discuss your knowledge on anticoagulants.

Write a note on potassium sparing diuretics. Q. 6 (a) Write synthesis of: (any three)

. Amantadine ii). Mefloquine iii). Thiotepa iv). Methotrexate

. Trimethoprim

Discuss in detail about chemical degradation of Penicillins.

Define scabies. Write a short note on antiscabies agents.

Write in detail about CADD.

Discuss in detail about diagnostic agents.

Write a short note on antipedicular agents.