What are aminoglycoside antibiotics? Give chemistry and SAR of aminoglycoside
[6 marks]Chemically classify Sulphonamide and Discuss its SAR
[4 marks]What are Fluoroquinolones? Classify them. Give the mechanism of action of Fluoroquinolone
[4 marks]Give source of any two broad spectrum antibiotics. Write short note on stereochemistry and SAR of Tetracycline.
[6 marks]Why azithromycin is better macrolide as compared to erythromycin? Discuss intramolecular ketal formation in erythromycin under acidic condition and its importance in degradation of erythromycin
[4 marks]Classify anti-HIV agents and write a note on reverse transcriptase inhibitors
[4 marks]What are antiprotozoal agents? Discuss the chemistry and SAR of 4- aminoquinolines.
[6 marks]Classify Antifungal agents, write short note on antifungal Antibiotics
[4 marks]Write synthesis of chloroquine and Isoniazid
[4 marks]Explain Lipophilic, steric and electronic parameter used in QSAR in detail.
[6 marks]Give the Application, Advantages and Disadvantages for combinatorial chemistry
[4 marks]Explain solid support synthesis and supports used in same.
[4 marks]Write chemical classification of oral hypoglycemic agents with suitable examples
[6 marks]Write a short note on anti-hyperlipidemic agents.
[4 marks]Classify anti-hypertensive agents with suitable examples. Q. 6 (a) Explain in detail about nomenclature and stereochemistry of steroids.
[6 marks]Write a short note on Angiotensin Converting Enzyme inhibitors.
[4 marks]Discuss in detail oral anticoagulants.
[4 marks]What do you mean by antineoplastic agents, classify them and discuss in details Alkylating agents.
[6 marks]What are diuretics? Classify diuretics with suitable examples
[4 marks]Classify anti-anginal agents. Describe the mechanism of action and use of nitrates
[4 marks]