Define and explain sedative and hypnotic drugs. Explain SAR of benzodiazepine in detail.
[6 marks]Write brief note on SAR of Sympathomimetic Agents with appropriate structural examples.
[5 marks]Explain the Structural Activity Relationship of Phenothiazines with examples.
[5 marks]Define Anticonvulsants. Give SAR of Anticonvulsants with appropriate examples.
[6 marks]State and explain Isosterism and Bioisosterism. Give a classification of Bioisosterism with appropriate examples.
[5 marks]Give brief accounts of the classification of Parasympathomimetic agents with appropriate structural examples.
[5 marks]Write a short note on the Classification of Antipsychotics giving suitable examples.
[6 marks]Draw the structure of i) Chlorprothixene ii) Thiothixene iii) Clozapine iv) Haloperidol v) Valproic acid
[5 marks]Write synthetic pathway of the following drugs: i) Propranolol ii) Phenylephrine
[5 marks]Explain the SAR of barbiturates in detail with structural examples.
[6 marks]Give the name and structure of any two-ring Analogues of Phenothiazines and Write the synthesis of Phenytoin.
[5 marks]Explain the synthetic pathway of the following drugs: i. Mefenamic acid ii. Ibuprofen
[5 marks]Enlist and give a brief note on the Physio-chemical parameter of drug affecting biological activity.
[6 marks]Write a short note on the SAR of Morphine with appropriate examples.
[5 marks]Write Synthesis of the following drugs: i. Salbutamol ii. Neostigmine Q. 6 (a) Write a note on NSAIDS giving appropriate structural examples
[6 marks]Give the name of any three Narcotic antagonists with its structures.
[5 marks]Write synthetic pathway of the following drugs: i) Tolazoline ii) Dicyclomine
[5 marks]Define Xenobiotics. Explain Phase-Ireaction metabolism with appropriate examples and mechanisms.
[6 marks]Give a Short note on volatile Inhalation Anesthetics.
[5 marks]Give a synthesis of barbital and Diazepam.
[5 marks]