Explain Introduction, History and Development of Medicinal Chemistry.
[6 marks]Write a note on bioisosterism.
[5 marks]Explain factors affecting drug metabolism including stereo chemical aspects.
[5 marks]Explain biosynthesis and catabolism of catecholamine.
[6 marks]Give stracture activity relationship of sympathomimetic agents.
[5 marks]Write a note on Phase-Ireactions in drug metabolism
[5 marks]Explain classification of Sympathomimetic agents .
[6 marks]Explain stracture activity relationship studies of Morphine and related drugs.
[5 marks]Give synthesis of Epinephrine and Salbutamol
[5 marks]Define adrenergic blockers. Explain SAR of beta (β)-blockers.
[6 marks]Write a note on narcotic antagonist
[5 marks]Write a note on solanaceous alkaloids and analogues.
[5 marks]Explain classification of Parasympathomimetic agents.
[6 marks]Explain stracture activity relationship of cholinolytic agents.
[5 marks]Give Synthesis of Neostigmine and Carbachol. Q. 6 (a) Classify Antipsychotics giving suitable examples.
[6 marks]Explain classification of Anticonvulsant drugs.
[5 marks]Write a note on non-steroidal anti-inflammatory drugs (NSAIDS).
[5 marks]Difference between sedative and hypnotics drugs. Explain SAR of benzodiazepine.
[6 marks]Give a synthesis of barbital and Diazepam.
[5 marks]Expain SAR of Phenothiazines with drug examples.
[5 marks]