Discuss various approaches used in drug design.
[6 marks]Write brief note on Combinatorial Chemistry.
[5 marks]What is QSAR? Give detailed note on Hansch model.
[5 marks]Classify Antimalarial Agents with examples and structures.
[6 marks]Discuss SAR of Quinolines.
[5 marks]Write note on concept and applications of Prodrugs.
[5 marks]Differentiate terms with examples: Bacteriostatics & Bactericidals. Write SAR of Cephalosporins.
[6 marks]Write short note on Chemistry of Aminoglycosides.
[5 marks]Discuss Chemistry and advantages of Semisynthetic Penicilins.
[5 marks]Comment on: “Tetracyclines should not be taken with milk”. Write SAR of Tetracyclines.
[6 marks]Give synthesis of Chloramphenicol and Chloroquine
[5 marks]Write short note on Macrolides.
[5 marks]What is MDR TB & XDR TB? Write a note on first-line Anti TB drugs.
[6 marks]Give synthesis of Isoniazid and Ciprofloxacin.
[5 marks]Write short note on Quinolones.
[5 marks]Explain in brief about Azoles as Antifungal Agents. Write synthesis of Tolnaftate.
[6 marks]Explain SAR of Sulphonamides. Write synthesis of Sulphamethoxazole.
[5 marks]Give the IUPAC name, synthesis and mechanism of Albendazole OR Mebendazole, an anthelmintic agent.
[5 marks]Write brief account on Antiamoebic Agents. Give synthesis of Metronidazole.
[6 marks]Give synthesis of Trimethoprim and Nitrofurantoin
[5 marks]Write detailed note on Antiviral Agents.
[5 marks]