Discuss Penicillins with classification and mechanism of action.
[6 marks]Write down the chemistry and SAR of sulphonamides.
[5 marks]Define beta lactam antibiotics and classify Cephalosporins with suitable examples.
[5 marks]Write brief note on SAR of Quinolones with structural examples.
[6 marks]Write uses and synthesis of the following drugs:
[5 marks]Acyclovir (ii) Para amino salicylic acid
[ marks]Write a note on Aminoglycosides.
[5 marks]Define and classify anti-tubercular agents with synthesis of Isoniazid.
[6 marks]Give the synthesis of following drugs. i. Chloroquine phosphate ii. Ciprofloxacin
[5 marks]Classify antiviral agents with structural examples of any five drugs.
[5 marks]Write structure, synthesis, use and mechanism of action of Chloramphenicol.
[6 marks]Write a note on basic concepts and application of prodrugs design.
[5 marks]Write down SAR of quinolines with structural examples.
[5 marks]What is malaria? How it spreads? Classify antimalarial drugs with examples.
[6 marks]Write down classification of Anthelmintic agents. Write down synthesis of Mebendazole.
[5 marks]Discuss mode of action, therapeutic uses and classification of Tetracyclines. Q. 6 (a) Explain in brief about azoles as antifungal agents. Give the synthesis of Miconazole.
[6 marks]Explain the mechanism of action of Co-trimoxazole. Write synthesis of Trimethoprim and Sulfamethoxazole.
[5 marks]Write a note on Macrolide.
[5 marks]Define combinatorial chemistry. Discuss concept and applications of combinatorial chemistry.
[6 marks]What is drug design? Give brief note on physicochemical parameters used in QSAR.
[5 marks]Write about molecular docking techniques.
[5 marks]