Write down chemical degradation β-Lactam antibiotics. Discuss about β- lactamase inhibitors.
[6 marks]Write down synthesis of Trimethoprim & Dapsone.
[5 marks]Write down SAR of Quinolones in details.
[5 marks]Write about etiology of malaria. Discuss classification of anti-malarial agents.
[6 marks]Discuss SAR of Tetracycline.
[5 marks]Explain about Pharmacophore modeling.
[5 marks]Define Prodrug. Discuss basic concepts and application of Prodrugs.
[6 marks]Write a note on antiviral agents in details.
[5 marks]Explain MDR-TB. Write a note on first-line anti tubercular agents.
[5 marks]Write down classification and SAR of Sulfonamides.
[6 marks]Write about mode of action, therapeutic uses and synthesis of Chloramphenicol.
[5 marks]Write a note on anti-protozoal agents.
[5 marks]Write down classification, mode of action and therapeutic uses of Aminoglycosides.
[6 marks]What is QSAR? Write about Hansch analysis in QSAR.
[5 marks]Write down synthesis of Chloroquine & Pamaquine. Q. 6 (a) Explain in brief about azoles as antifungal agents. Give the synthesis of Miconazole.
[6 marks]Discuss various approaches used in drug design.
[5 marks]Explain about XDR TB. Write down synthesis of Isoniazid.
[5 marks]Define combinatorial chemistry. Discuss concept and applications of combinatorial chemistry.
[6 marks]Write down classification of Anthelmintic agents. Write down synthesis of Mebendazole.
[5 marks]Write down SAR of Macrolide.
[5 marks]