Classify cephalosporin. Write a note on monobactam.
[6 marks]Define and classify prodrug with suitable examples.
[5 marks]What is QSAR? Write a note on Hansch analysis.
[5 marks]What is combinatorial chemistry? Explain different methodologies used for synthesis.
[6 marks]Classify sulphonamides based on chemical structures. Outline synthesis of sulphamethoxazole.
[5 marks]Explain SAR of Sulphonamides.
[5 marks]Classify antitubercular agent. Give synthesis of Isoniazid.
[6 marks]Write short notes on computer aided drug design.
[5 marks]Describe SAR of quinolines. Explain mechanism of chloroquine.
[5 marks]i. Life cycle of malarial parasite ii. Macrolide antibiotic
[6 marks]Write a note on applications of prodrug.
[5 marks]Write IUPAC name and synthesis of the following drugs :
[5 marks]Miconazole (ii) Mebendazole
[ marks]Give brief note on antiviral agents.
[6 marks]Write the chemical degradation of penicillin with structures.
[5 marks]Explain SAR of quinolones as antibacterial agent. Q. 6 (a) Classify and explain mechanism of action of azole antifungal agents. Draw structure of one drug from each class of it.
[6 marks]Write uses and synthesis of the following drugs :
[5 marks]Ciprofloxacin (ii) Acyclovir
[ marks]Draw general structure of tetracycline antibiotics. Explain mechanism of action and side effects of it.
[5 marks]i. What is tissue amoebicide and luminal amoebicid? Give examples. ii. Outline the synthesis of metronidazole. iii. What is anthelmintic? Explain mechanism of benzimidazole as anthelmintic.
[6 marks]Write a short note on aminoglycoside antibiotics.
[6 marks]Give IUPAC name and synthesis of the following drugs :
[6 marks]Chloroquine (ii) Chloramphenicol
[ marks]