Discuss mode of action, therapeutic uses and chemical degradation of Tetracycline.
[6 marks]Write down SAR of Cephalosporin anti-biotic.
[5 marks]Write a note of Aminoglycosides.
[5 marks]Define Prodrugs. Discuss basic concepts and application of prodrugs design.
[6 marks]Write down SAR of quinolines. Write down synthesis of Chloroquine.
[5 marks]Write down mechanism of action, therapeutic uses and synthesis of Chloramphenicol.
[5 marks]Classification of Anti-tubercular agents. Discuss about DOTS therapy in Tuberculosis.
[6 marks]Write down SAR of quinolones.
[5 marks]Write a note on drugs used for the treatment of HIV. Discuss synthesis of Acyclovir.
[5 marks]Write about SAR and classification of Sulfonamides.
[6 marks]Define QSAR. Discuss about Hansch QSAR Models in details.
[5 marks]Write about pharmacophore modeling in drug design.
[5 marks]Classify antifungal agents. Write down mode of action and therapeutic use of azole class of antifungal agents.
[6 marks]Write down synthesis, mode of action and uses of Dapsone.
[5 marks]Write a note of Macrolide anti-biotic. Q. 6 (a) Define combinatorial chemistry. Discuss concepts and application of combinatorial chemistry.
[6 marks]Write a note on Anthelmintics. Write down synthesis of Mebendazole.
[5 marks]Write about etiology of malaria.
[5 marks]Discuss various approaches used in drug design.
[6 marks]Write a note on anti-protozoal agents. Discuss synthesis of Metronidazole.
[5 marks]Write about molecular docking techniques.
[5 marks]