Explain Occupational theory and Induced fit theory of receptor in detail.
[6 marks]Enlist and explain factors affecting drug-receptor interaction.
[5 marks]Write note on phase - II metabolic pathways.
[5 marks]Write differences between opioid and non-opioid analgesics. Discuss SAR of phenothiazines.
[6 marks]What is drug metabolism? Describe various sites of drug metabolism.
[5 marks]Write the synthetic steps of Mefenamic acid and Diclofenac.
[5 marks]Define and classify CNS stimulants. Write a note on analeptics.
[6 marks]Define Insomnia. Explain mechanism and structure activity relationship of Barbiturates derivatives.
[5 marks]Give synthesis of L-Dopa and Chlordiazepoxide.
[5 marks]What is Parkinsons disease? Write a note on antiparkinson’s agents.
[6 marks]What is enzymes p-450? Explain catalytic reaction cycle involviong them.
[5 marks]Write note on cognition enhancers.
[5 marks]Write a note on anti-anxiety agents.
[6 marks]Classify the NSAIDs with chemical structures.
[5 marks]Write a note on Disease Modifying Anti-Rheumatoid Drugs. Q. 6 (a) Write the medicinal chemistry of inhalational anesthetics.
[6 marks]Write the synthesis, IUPAC name and uses of Imipramine.
[5 marks]Give IUPAC name and synthesis of the following drugs : (i) Lignocaine (ii) Indomethacin (iii) Diclofenac
[5 marks]Write short notes on DMARDS.
[6 marks]Explain Phase Ireactions of drug metabolism in brief.
[5 marks]Discuss the structure-activity relationship of tricyclic antidepressants.
[5 marks]