Define sedatives and hypnotics. Classify with examples. Discuss general method of synthesis of barbiturates.
[6 marks]Discuss SAR of local anesthetics having amide linkage in their structures.
[5 marks]What is Alzheimer’s disease? Discuss its cause and treatment.
[5 marks]What is Phase-II metabolism? How glucoronide conjugation helps to metabolized drug molecules. Explain with examples.
[6 marks]Write note on anti-gout drugs.
[5 marks]Write synthesis of Lignocaine and discuss its mode of action.
[5 marks]Enlist and explain factors affecting drug-receptor interaction.
[6 marks]Explain Various Forces involved in Drug-Receptor Interaction
[5 marks]Write synthesis of i) Halothane ii ) Chlorpromazine
[5 marks]Write synthesis of any two: 1) Ibuprofen 2) Nimesulide 3) Phenytoin
[6 marks]Classify and Explain Hallucinogens in detail.
[5 marks]Write synthesis of i) L-Dopa ii) Diclofenac
[5 marks]Describe various forces involved in drug receptor interaction with examples.
[6 marks]Discuss SAR of Tricyclic Antidepressant drugs with suitable example.
[5 marks]Write synthesis of drugs i) xylocaine ii) Thiopental sodium Q. 6 (a) Define antipsychotic agents. Write detailed SAR of phenothiazines.
[6 marks]Explain different types of epilepsy. Classify epileptic agents with examples.
[5 marks]Write note on anti-anxiety agents.
[5 marks]Write short notes on analeptic agents.
[6 marks]What are CNS dipressants. Write SAR of butyrophenones.
[5 marks]What is Cytochrome P-450? Explain its role and function in Xenobiotic Metabolism
[5 marks]