Write in brief about different theories of drug receptor interactions.
[6 marks]Discuss the factors affecting drug receptor interactions.
[5 marks]How drug metabolism is helpful in drug design.
[5 marks]Explain Phase Ireactions of drug metabolism in brief.
[6 marks]What is CYP450 and give its importance.
[5 marks]Write SAR of tricyclic antidepressants.
[5 marks]Explain Analeptics and Hallucinogens. Give synthesis of Imipramine.
[6 marks]What is epilepsy ? Classify antiepileptics with examples. Give synthesis of Phenytoin.
[5 marks]Define hypnotics and sedatives and give SAR of barbiturate derivatives.
[5 marks]Classify local anesthetics with examples. Write their mechanism of action.
[6 marks]What do you mean by psychiatric disease? Give SAR of Phenothiazines.
[5 marks]Write short notes on DMARDS.
[5 marks]Give IUPAC name and synthesis of the following drugs :
[6 marks]Lignocaine (ii) Indomethacin (iii) Diclofenac
[ marks]Write short note on Alzheimer’s disease.
[5 marks]Classify NSAIDs and give their mechanism of action. Q. 6 (a) What are different reasons of Parkinson’s disease. Give synthesis of L-dopa.
[6 marks]Explain the term receptor and write about different types of receptors.
[5 marks]Write short note on cognition enhancers.
[5 marks]Write IUPAC name and synthesis of the following drugs :
[6 marks]Phenobarbitone (ii) Thiopentone sodium (ii) Carbamazepine.
[ marks]Explain in brief factors affecting drug metabolism.
[5 marks]Write in short about conjugation reactions of drug metabolism.
[5 marks]